Eurobusones A-D, four antibacterial formyl phloroglucinol meoterpenoids from Eucalyptus robusta
Liu, Rui 1Liu, Xiang-Yue 1Li, Min Liu, Juan Yang, Ming-Hua Kong, Ling-Yi
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作者信息
1. China Pharmaceut Univ
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Abstract
Four antibacterial formyl phloroglucinol memterpenoids (FPMs), eurobusones A-D (1-4), as well as six known analogues (5-10), were isolated from the leaves of Eucalyptus robusta. Their structures were determined by the analysis of spectroscopic data and electron circular dichroism (ECD) calculation, along with the application of Snatzke helicity rules. Among them, compounds 2 and 8-10 showed good activity against Staphylococcus aureus, Pseudomonas aeruginosa and Bacillus subtilis with MIC50 values less than 1.00 mu g/mL.
NSTL
Elsevier