首页|Hybrid-based drug design of 1,2,3-triazole-pyrimidine-hybrid derivatives: Efficient inhibiting agents of mesenchymal-epithelial transition factor reducing gastric cancer cell growth
Hybrid-based drug design of 1,2,3-triazole-pyrimidine-hybrid derivatives: Efficient inhibiting agents of mesenchymal-epithelial transition factor reducing gastric cancer cell growth
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NSTL
Sage
Anti-gastric cancer activity of 18 synthesized compounds was studied using theoretical and computational method. The studied compounds were docked against mesenchymal-epithelial transition factor (PDB ID: 2wgj) and the obtained scoring was compared with the standard used. Thus, all the studied compounds were efficient than the standard (5-florouracil); also, A9 proved to be more effective than other studied compounds.
NSTL
Sage
