首页|Enzyme assisted enantioselective synthesis of the alkaloid (+)-aloperine
Enzyme assisted enantioselective synthesis of the alkaloid (+)-aloperine
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The enantioselective synthesis of the lupinine alkaloid (+)-aloperine is described. The synthetic scheme presents three steps that are mediated by enzymes: kinetic resolution, oxidation of a primary alcohol to an aldehyde and oxidation of a secondary alcohol to a ketone. (C) 2004 Elsevier Ltd. All rights reserved.