首页|Grass-like Pt-doped NiCo2O4 modified electrode for electrochemical detection of amlodipine
Grass-like Pt-doped NiCo2O4 modified electrode for electrochemical detection of amlodipine
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NSTL
Elsevier
In this paper, a synthesis of a novel grass-like Pt-doped NiCo2O4 nanocomposite (GL Pt-doped NiCo2O4) is demonstrated. The characterization of fabricated nanocomposite was performed using the techniques such as scanning electron microscope (SEM), Energy-dispersive X-ray spectroscopy (EDX) and X-ray diffraction (XRD). Further, this nanocomposite was used for the modification of screen-printed electrode (SPE). A suitable electrocatalytic behavior was obtained for GL Pt-doped NiCo2O4/SPE to detect amlodipine (AML) selectively and sensitively in presence of different routine interfering ions and physiological compounds. The AML determination showed broad linearity (0.07 to 350 mu M) using differential pulse voltammetry (DPV), and limit of detection (LOD) and limit of quantification (LOQ) of 0.009 and 0.027 mu M were obtained respectively. Moreover, acceptable recovery for AML by the present modified electrode was obtained in drug and biological samples.
NSTL
Elsevier
