首页|CHROMONE DERIVATIVES OF Cassia pumila AND THEIR ANTI-MRSA ACTIVITY
CHROMONE DERIVATIVES OF Cassia pumila AND THEIR ANTI-MRSA ACTIVITY
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NSTL
Two new (1 and 2) compounds, together with five known (3-7) chromone derivatives, were isolated from the whole plants of Cassia pumila. Their structures were elucidated by spectroscopic methods, including extensive ID and 2D NMR techniques. Compounds 1-7 were evaluated for their anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) activity. The results revealed that compounds 1, 2, 5, and 6 showed good inhibition with IZD of 13.4 ± 2.5, 12.2 ± 2.0, 14.6 ± 2.2, and 14.2 ± 2.6 mm, and compounds 3, 4, and 7 showed weak inhibition with IZD of 10.7 ± 2.2, 11.3 ± 2.0, and 10.8 ± 2.1 mm, respectively.
NSTL
