Three new sesquiterpenoids, gingerterpenes B-D (1-3), two new diterpenoids, gingerterpenes E-F (4-5), and two known sesquiterpenoids (6-7) were isolated from Zingiberis Rhizoma. The structures of com-pounds (1-5) were determined by their 1D-NMR, 2D-NMR data and mass spectrometry. Their absolute configurations were determined by comparing their experimental and theoretically calculated ECD curve and quantum mechanical (QM) NMR approach. Compounds 2-7 were evaluated their cell viability, anti-apoptosis levels on human normal lung bronchial epithelial cells, which induced by lipopolysaccharide at 10 lM. (c) 2022 Elsevier Ltd. All rights reserved.
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