Brain injury2022，Vol.36Issue(6) ：10.DOI:10.1080/02699052.2022.2077442

The association between hematologic parameters and intracranial injuries in pediatric patients with traumatic brain injury Running title: Haematologic parameters in paediatric head trauma

Eser, Pinar Corabay, Seniha Ocakoglu, Gokhan Taskapilioglu, Mevlut Ozgur Ozmarasali, Ali Imran
Brain injury2022，Vol.36Issue(6) ：10.DOI:10.1080/02699052.2022.2077442
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  • NSTL
  • Taylor & Francis

The association between hematologic parameters and intracranial injuries in pediatric patients with traumatic brain injury Running title: Haematologic parameters in paediatric head trauma

Eser, Pinar 1Corabay, Seniha 2Ocakoglu, Gokhan 2Taskapilioglu, Mevlut Ozgur 1Ozmarasali, Ali Imran1
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作者信息

  • 1. Dept Neurosurg,Bursa Uludag Univ
  • 2. Dept Biostat,Bursa Uludag Univ
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Abstract

Objective Analyzing the association between hematologic parameters and abnormal cranial computerized tomography (CT) findings after head trauma. Material and methods A total of 287 children with isolated traumatic brain injury (TBI) were divided into the 'normal' (NG), 'linear fracture' (LFG) and 'intraparenchymal injury' groups (IPG) based on head CT findings. Demographical/clinical data and laboratory results were obtained from medical records. Results The neutrophil-lymphocyte ratio was markedly higher in the LFG (p = 0.010 and p = 0.016, respectively) and IPG (p = 0.004 and p < 0.001, respectively) compared with NG. Lower lymphocyte-monocyte ratio (p = 0.044) and higher red cell distribution width-platelet ratio (RPR) (p = 0.030) were associated with intraparenchymal injuries. Patients requiring neurosurgical intervention had higher neutrophil-lymphocyte ratio (p = 0.026) and RPR values (p = 0.031) and lower platelet counts (p = 0.035). Lower levels of erythrocytes (p = 0.005), hemoglobin (p = 0.003) and hematocrit (p = 0.002) were associated with severe TBI and unfavorable outcome (p = 0.012, p = 0.004 and p = 0.006, respectively). Conclusions Hematologic parameters are useful in predicting the presence of abnormal cranial CT findings in children with TBI in association with injury severity; surgery need and clinical outcome.

Key words

Glasgow coma score/hematologic markers/neurosurgery/outcome/pediatric patients/traumatic brain injury/GLASGOW COMA SCALE/CELL DISTRIBUTION WIDTH/TO-LYMPHOCYTE RATIO/COMPUTED-TOMOGRAPHY/RADIATION-EXPOSURE/MOTOR SCORE/NEUTROPHIL/MILD/ANEMIA/MANAGEMENT

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出版年

2022
Brain injury

Brain injury

SCI
ISSN：0269-9052
被引量1
参考文献量70
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