首页|The association between hematologic parameters and intracranial injuries in pediatric patients with traumatic brain injury Running title: Haematologic parameters in paediatric head trauma

The association between hematologic parameters and intracranial injuries in pediatric patients with traumatic brain injury Running title: Haematologic parameters in paediatric head trauma

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Objective Analyzing the association between hematologic parameters and abnormal cranial computerized tomography (CT) findings after head trauma。 Material and methods A total of 287 children with isolated traumatic brain injury (TBI) were divided into the 'normal' (NG), 'linear fracture' (LFG) and 'intraparenchymal injury' groups (IPG) based on head CT findings。 Demographical/clinical data and laboratory results were obtained from medical records。 Results The neutrophil-lymphocyte ratio was markedly higher in the LFG (p = 0。010 and p = 0。016, respectively) and IPG (p = 0。004 and p < 0。001, respectively) compared with NG。 Lower lymphocyte-monocyte ratio (p = 0。044) and higher red cell distribution width-platelet ratio (RPR) (p = 0。030) were associated with intraparenchymal injuries。 Patients requiring neurosurgical intervention had higher neutrophil-lymphocyte ratio (p = 0。026) and RPR values (p = 0。031) and lower platelet counts (p = 0。035)。 Lower levels of erythrocytes (p = 0。005), hemoglobin (p = 0。003) and hematocrit (p = 0。002) were associated with severe TBI and unfavorable outcome (p = 0。012, p = 0。004 and p = 0。006, respectively)。 Conclusions Hematologic parameters are useful in predicting the presence of abnormal cranial CT findings in children with TBI in association with injury severity; surgery need and clinical outcome。

Glasgow coma scorehematologic markersneurosurgeryoutcomepediatric patientstraumatic brain injuryGLASGOW COMA SCALECELL DISTRIBUTION WIDTHTO-LYMPHOCYTE RATIOCOMPUTED-TOMOGRAPHYRADIATION-EXPOSUREMOTOR SCORENEUTROPHILMILDANEMIAMANAGEMENT

Eser, Pinar、Corabay, Seniha、Ocakoglu, Gokhan、Taskapilioglu, Mevlut Ozgur、Ozmarasali, Ali Imran

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Dept Neurosurg,Bursa Uludag Univ

Dept Biostat,Bursa Uludag Univ

2022

Brain injury

Brain injury

SCI
ISSN:0269-9052
年,卷(期):2022.36(6)
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