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Acinetobacter baumannii: More ways to die

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  • NSTL
  • Elsevier
Acinetobacter baumannii is an important nosocomial and opportunistic pathogen. It causes infections worldwide, especially in intensive care units. It is clinically significant owing to its ability to persist for long periods on surfaces, as well as its resistance to multiple antibiotics. This pathogen has been reported to defy the available therapeutic options to combat it. In this dire circumstance, the need for new approaches to treating A. baumannii infections is undeniable. In this minireview, we summarize three important treatment options for controlling A. baumannii pathogen, including the use of bacteriophage / bacteriophage cocktails, phage-antibiotic combinations and resistance-driven fitness losses. It is hoped that, as resources to treat its infection expand, A. baumannii can become less scary.

Acinetobacter baumanniiAntimicrobial resistancePhage resistanceFitness costsPhage cocktailsPhage-antibiotic combinationCOLISTIN-RESISTANCEANTIMICROBIAL RESISTANCENOSOCOMIAL INFECTIONSIMPAIRED VIRULENCEBIOLOGICAL COSTPHAGE THERAPYMECHANISMSFITNESSBACTERIOPHAGESIMPACT

Oyejobi, Greater Kayode、Olaniyan, Sunday Olabode、Yusuf, Nana-Aishat、Ojewande, Deborah Adepeju、Awopetu, Mobolaji Johnson、Oyeniran, Goodness Opeyemi、Khan, Fazal Mehmood、Dare, Peter Alabi、Adegbite-Badmus, Maryam Kikelomo

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Osun State Univ

Org African Acad Doctors

Shenzhen Univ

Redeemers Univ

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2022

10.1016/j.micres.2022.127069

Microbiological Research

Microbiological Research

EISCI
ISSN：0944-5013
年,卷(期)：2022.261
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