首页|Synthesis and in vitro evaluation of the antifungal activities of dihydropyrimidinones.

Synthesis and in vitro evaluation of the antifungal activities of dihydropyrimidinones.

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Copper (II) chloride in the absence of any solvent, efficiently catalyses the synthesis of dihydropyrimidinones (80-96% yields) by the Biginelli reaction. Six compounds were selected and examined their antifungal activities against the radial growth of three fungal species viz., Trichoderma hammatum, Trichoderma koningii and Aspergillus niger.

SynthesisEvaluationTrichodermaIn VitroChloride Ion木霉属

Singh OM、Singh SJ、Devi MB、Devi LN、Singh NI、Lee SG

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Department of Chemistry, Manipur University, Canchipur, Imphal 795003, Manipur, India. ok_mukherjee@yahoo.co.in

2008

Bioorganic and Medicinal Chemistry Letters

Bioorganic and Medicinal Chemistry Letters

ISSN:0960-894X
年,卷(期):2008.18(24)