首页|Neuroprotective effects of flavones on hydrogen peroxide-induced apoptosis in SH-SY5Y neuroblostoma cells.

Neuroprotective effects of flavones on hydrogen peroxide-induced apoptosis in SH-SY5Y neuroblostoma cells.

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Neuroprotective effects of flavones were examined. Luteolin and apigenin exhibited neuroprotection against oxidative stress-induced cell death in SH-SY5Y cells. Free radical scavenging activity and neuroprotection assays revealed that flavones exerted their neuroprotective effects via the direct interaction with the apoptotic caspase pathway independently of their antioxidant activity.

FlavonesneuroprotectionApoptosisHydrogen Peroxideapigenin黄酮类脱噬作用过氧化氢

Kang SS、Lee JY、Choi YK、Kim GS、Han BH

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College of Pharmacy and Natural Products Research Institute, Seoul National University, Seoul 110-460, South Korea.

2004

Bioorganic and Medicinal Chemistry Letters

Bioorganic and Medicinal Chemistry Letters

ISSN:0960-894X
年,卷(期):2004.14(9)