Efficient synthesis of zealexin B1, a maize sesquiterpenoid phytoalexin, via Suzuki-Miyaura coupling
Matsushima, Yoshitaka 1Ishii, Kohei 1Huffaker, Alisa 2Schmelz, Eric A.2
扫码查看
点击上方二维码区域，可以放大扫码查看
作者信息
1. Tokyo Univ Agr
2. Univ Calif San Diego
折叠
Abstract
The first concise method for the synthesis of zealexin B1, a maize sesquiterpenoid phytoalexin, was developed via Suzuki-Miyaura coupling. The coupling components were prepared as their corresponding triflates or boronates, starting from the corresponding commercially available ketone and a known ketoester; the latter is a Diels-Alder product. The reaction was also performed by interchanging the boronate and triflate coupling partners, and the yields were significantly different for the two combinations. (C) 2022 Elsevier Ltd. All rights reserved.
NSTL
Elsevier