首页|Positive Attributes of Anti-TERT CD4 T-Helper Type 1 Immune Responses in Melanoma

Positive Attributes of Anti-TERT CD4 T-Helper Type 1 Immune Responses in Melanoma

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Nardin et al's (2021) study on melanoma reports anti-TERT CD4 T helper type (Th) 1 responses in more than half of patients. Besides indicating a trend for improved survival, increased anti-TERT CD4 Th1 responses predicted better outcomes for patients treated with immune checkpoint inhibitors. Thus, harnessing systemic anti-TERT CD4 Th1 responses together with tumor-specific elevation of telomerase can potentially open new avenues for biomarkers and treatment in melanoma.

Kumar, Rajiv、Nagore, Eduardo、Viros, Amaya

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Div Funct Genome Anal,German Canc Res Ctr

Dept Dermatol,Inst Valenciano Oncol

Canc Res UK Manchester Inst,Univ Manchester

2022

The Journal of investigative dermatology.

The Journal of investigative dermatology.

ISSN:0022-202X
年,卷(期):2022.142(2)