Does tetanus vaccination contribute to reduced severity of the COVID-19 infection?
Rickett, Christopher D. 1Maschhoff, Kristyn J. 1Sukumar, Sreenivas R.1
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作者信息
1. Hewlett Packard Enterprise, Seattle, WA USA
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Abstract
We present the hypothesis to the scientific community actively designing clinical trials and recommending public health guidelines to control the pandemic that "Tetanus vaccination may be contributing to reduced severity of the COVID-19 infection" - and urge further research to validate or invalidate the effectiveness of the tetanus toxoid vaccine against COVID-19. This hypothesis was revealed by an explainable artificial intelligence system unleashed on open public biomedical datasets. As a foundation for scientific rigor, we describe the data and the artificial intelligence system, document the provenance and methodology used to derive the hypothesis and also gather potentially relevant data/evidence from recent studies. We conclude that while correlations may not be reason for causation, correlations from multiple sources is more than a serendipitous coincidence that is worthy of further and deeper investigation.
NSTL
Elsevier