A mild, practical, eco-friendly and environmentally friendly electrochemical synthesis method of p-aminovinyl sulfone and carbonyl sulfones from sulfonyl hydrazide and enamides has been developed. This transformation only requires electrolytes and solvent, thus avoids transition metal catalysts, stoichiometric oxidant and base. Two different types of sulfone derivatives can be obtained only by changing the reaction solvent. This transformation also features mild conditions (room temperature, air), broad substrate scopes, and excellent stereoselectivities in mild to good yield. (c) 2021 Elsevier Ltd. All rights reserved.
Key words
p -aminovinyl sulfone/Carbonyl sulfones/Electrochemical synthesis/Excellent stereoselectivities/CATALYZED HYDROGENATION/FUNCTIONALIZATION
NSTL
Elsevier