首页|New cytotoxic quinone analogues from the rhizomes of Arnebia euchroma

New cytotoxic quinone analogues from the rhizomes of Arnebia euchroma

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  • NSTL
  • Elsevier
? 2022 Phytochemical Society of EuropeTwo new quinone analogues, given the trivial names arneromas A–B (1–2) were isolated from the rhizome of Arnebia euchroma. Their structures were elucidated on the basis of extensive spectroscopic analyses. The absolute configurations of both compounds were determined by comparison of their calculated and experimental CD curves. In addition, compounds 1–2 were tested for their cytotoxic activities against HCT-8 and HL-60 cancer cell lines, and both of the compounds showed moderate inhibitory activities against HL-60 cell line with IC50 values of 9.1 and 7.2 μM, respectively.

Arnebia euchromaCytotoxic activitiesMonoterpenylbenzoquinoneZicao

Song J.、Chen Y.、Li L.、Ye J.、Dong W.、Dong H.-Y.、Song B.、Wang J.、Wang Z.-C.、Gao W.-B.

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Qiqihar Medical University

Cangzhou Normal University

2022

10.1016/j.phytol.2022.04.010

Phytochemistry Letters

Phytochemistry Letters

SCI
ISSN：1874-3900
年,卷(期)：2022.50
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