Tetrahedron letters2022，Vol.1003.DOI:10.1016/j.tetlet.2022.153874

Facile one-pot three-component strategy for the synthesis of 2-amino-4-arylthiazoles via elemental sulfur source

Luo, Min Kang, Li Tang, Long-Xing Liang, Qing Liu, Yuan-Lin Yang, Zi Zhang, Chun-Tao Peng, Cai-Yun Fu, Rong-Geng Liang, Xiao-Ping
Tetrahedron letters2022，Vol.1003.DOI:10.1016/j.tetlet.2022.153874
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  • NSTL
  • Elsevier

Facile one-pot three-component strategy for the synthesis of 2-amino-4-arylthiazoles via elemental sulfur source

Luo, Min 1Kang, Li 1Tang, Long-Xing 1Liang, Qing 1Liu, Yuan-Lin 1Yang, Zi 2Zhang, Chun-Tao 1Peng, Cai-Yun 1Fu, Rong-Geng 1Liang, Xiao-Ping1
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作者信息

  • 1. Hunan Univ Chinese Med
  • 2. Changsha Med Univ
  • 折叠

Abstract

A novel and facile metal-free method for the green synthesis of 2-amino-4-arylthiazole derivatives through the three-component cascade reaction of aromatic methyl ketones, elemental sulfur and cyanamide is reported. One C-N bond and two C-S bonds were formed in one-pot protocol without using catalysts. (C) 2022 Elsevier Ltd. All rights reserved.

Key words

2-amino-4-arylthiazole/Elemental sulfur/Three-component reaction/Cyclization/BIOLOGICAL EVALUATION/ALPHA-DIAZOKETONES/DERIVATIVES/ACCESS/THIOUREAS/KETONES/DESIGN

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出版年

2022
Tetrahedron letters

Tetrahedron letters

CCR
ISSN：0040-4039
参考文献量30
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