首页|IN VIVO TEMPERATURE RISE MEASUREMENTS OF RABBIT LIVER AND FEMUR BONE SURFACE EXPOSED TO AN ACOUSTIC RADIATION FORCE IMPULSE

IN VIVO TEMPERATURE RISE MEASUREMENTS OF RABBIT LIVER AND FEMUR BONE SURFACE EXPOSED TO AN ACOUSTIC RADIATION FORCE IMPULSE

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  • NSTL
  • Elsevier
Acoustic radiation force impulse (ARFI) imaging and shear wave elastography use a "push pulse. " The push pulse, which is referenced as an ARFI in this study, has a longer duration than that of conventional diagnostic pulses (several microseconds). Therefore, there are concerns regarding thermal safety in vivo. However, few in vivo studies have been conducted using living animals. In this study, to suggest a concept for deciding an ARFI output and cooling time while considering thermal safety, the liver (with and without an ultrasound contrast agent) and femur bone surface of living rabbits were exposed to an ARFI, and the maximum temperature rise, temperature rise for 5-min duration, and cooling time were measured via a thermocouple. While testing within the regulation limits of diagnostic ultrasound outputs, a maximum temperature rise on the femur bone surface exceeded the allowable temperature rise (1.5C) in the British Medical Ultrasound Society (BMUS) statement. However, using the linear relationships between the pulse intensity integral (PII) of a single pulse and the above three temperature parameters, PII may be determined so that the maximum temperature rise is within the allowable temperature rise in the BMUS statement. The cooling time can be estimated from the PII. (E-mail: n.nitta@aist.go.jp) (C) 2022 World Federation for Ultrasound in Medicine & Biology. All rights reserved.

Acoustic radiation force impulseThermal safetyDifferent exposure conditionsTemperature riseCooling timeRabbitLiverUltrasound contrast agentFemur bone surfacePulse intensity integralTRANSIENT TEMPERATURE RISEMECHANICAL INDEXULTRASOUNDELEVATIONTISSUESAFETYHEART

Nitta, N. A. O. T. A. K. A.、Ishiguro, Y. A. S. U. N. A. O.、Sasanuma, H. I. D. E. K. I.、Takayama, N. O. R. I. Y. A.、Rifu, K. A. Z. U. M. A.、Taniguchi, N. O. B. U. Y. U. K., I、Akiyama, I. W. A. K. I.

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Natl Inst Adv Ind Sci & Technol,Hlth & Med Res Inst

Dept Surg,Jichi Med Univ

Dept Clin Lab Med,Jichi Med Univ

Med Ultrasound Res Ctr,Doshisha Univ

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2022

10.1016/j.ultrasmedbio.2022.02.019

Ultrasound in Medicine and Biology

Ultrasound in Medicine and Biology

EISCI
ISSN：0301-5629
年,卷(期)：2022.48(7)
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