首页|IMMUNOSUPPRESSIVE POLYKETIDES FROM THE MANGROVE ENDOPHYTIC FUNGUS Pestalotiopsis sp.HHL-I4
IMMUNOSUPPRESSIVE POLYKETIDES FROM THE MANGROVE ENDOPHYTIC FUNGUS Pestalotiopsis sp.HHL-I4
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NSTL
Marine endophytic fungi,including mangrove fungi,have attracted considerable interest as a potential source of bioactive natural products and have contributed significantly to drug discovery(1,2).One of the fungal genus that is especially productive with regard to the accumulation of a diverse array of mostly bioactive compounds is Pestalotiopsis(2,3).The literature has revealed that the most abundant metabolic types of genus Pestalotiopsis sp.are alkaloids,steroids,terpenoids,coumarins,chromones,quinines,and lactones.Most of them are potential leads for the treatment of human diseases and control of plant diseases.Bioassays have disclosed that antifungal(4),antimalaria(5),phytotoxic(6),cytotoxic(7),anti-HIV(8),antimicrobial(9),and plant-growth regulating(10)activities are the most notable bioactivities of secondary metabolites isolated from this genus.These compounds may have potential applications in modern medicine,agriculture,and the food industry.
Wen-Fang Zhang、Jian-Kun Ma、Xue-Xia Zhang
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One Health Institute,School of Chemical Engineering and Technology,Hainan University,570228,Haikou,P R,China
NSTL
