首页|A miniaturized, low-cost lens tube based laser-induced fluorescence detection system for automated microfluidic analysis of primary amines
A miniaturized, low-cost lens tube based laser-induced fluorescence detection system for automated microfluidic analysis of primary amines
扫码查看
点击上方二维码区域，可以放大扫码查看
原文链接
NSTL
Elsevier
? 2022In situ analyses are essential to ascertain potential past or present habitability in celestial bodies. One technique that provides the sensitivity and miniaturization needed to successfully detect trace organics in the outer Solar System is laser-induced fluorescence (LIF) detection, which, when coupled with microfluidic systems, provides a powerful wet chemistry platform that can meet the size and resource consumption constraints of a remote analysis mission. Herein, a portable LIF detection module (44-mm long, 18-mm wide) was prototyped and utilized to quantify bulk organics in a liquid sample via manual and automated analysis utilizing a programmable microfluidic architecture. The experimental limit of detection (LOD) for primary amines was 11.8 μM. A sample (Y31B) collected from the Atacama Desert in Yungay, Chile, was analyzed manually and found to contain 300 ± 50 μM of bulk primary amine organics, while the automated microfluidic protocol found the sample to contain 289 ± 4 μM of primary amines. Automated analyses showed no statistically significant differences when compared to the manual analyses (t-test, C.I. 95%). Our results demonstrate that the coupling of programmable microfluidic devices with a custom lens tube-based LIF detector enables automated analysis of primary amines using a protocol appropriate for remote analyses. This technique is an invaluable tool for in situ analysis applications in distant, resource-restricted environments.
AminesFluorescamine dyeLaser-induced fluorescence detectionPacific blue dyePlanetary scienceProgrammable microfluidic architectures
NSTL
Elsevier
