首页|Heterogeneous enantioselective hydrogenation of an unsaturated carboxylic acid over Pd supported on amine-functionalized silica
Heterogeneous enantioselective hydrogenation of an unsaturated carboxylic acid over Pd supported on amine-functionalized silica
扫码查看
点击上方二维码区域，可以放大扫码查看
原文链接
NSTL
The heterogeneous enantioselective hydrogenation of the C=C bond of aliphatic a,p-unsaturated carboxylic acids is a key asymmetric catalytic reaction because of its application in the production of pharmaceuticals.In this study,we investigated the enantioselective hydrogenation of(E)-2-methyl-2-butenoic acid over I cinchonidine-modified Pd catalysts.To improve the catalytic performance,a support material,mesocellular silica foam(MCF),was functionalized by grafting with primary amines.The use of the amine-functionalized MCF(NH2-MCF)support resulted in enhanced activity and enantioselectivity.The promoting effects originated from the increased electron density of the Pd nanoparticles and the selective blocking of low-coordinated Pd sites by the strong interaction of the amine groups with Pd nanoparticles.Promisingly,the Pd/NH2-MCF catalyst maintained its enantioselectivity over five successive cycles,thus demonstrating the reusability.Our results provide insights into the origin of the promoting effects of amine-functionalized supports and offer a strategy for improving supported catalysts for structure-sensitive reactions.
NSTL
