首页|Is the oral cavity a reservoir for prolonged SARS-CoV-2 shedding?
Is the oral cavity a reservoir for prolonged SARS-CoV-2 shedding?
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NSTL
Elsevier
Limited knowledge about the contagiosity and case fatality rate of COVID-19 as well as the still enigmatic route of transmission have led to strict limitations of non-emergency health care especially in head and neck medicine and dentistry。 There are theories that the oral cavity provides a favorable environment for SARS-CoV-2 entry and persistence which may be a risk for prolonged virus shedding。 However， intraoral innate immune mechanisms provide antiviral effects against a myriad of pathogenic viruses。 Initial hints of their efficacy against SARS-CoV-2 are surfacing。 It is hypothesized that intraoral immune system activity modulates the invasion pattern of SARS-CoV-2 into oral cells。 Thus， the significance of intraoral tissues for SARS-CoV-2 transmission and persistence cannot be assessed。
SARS-CoV-2COVID-19ContagiosityOral tissues
Troeltzsch, Matthias、Berndt, Ronald、Troeltzsch, Markus
NSTL
Elsevier
