Medical hypotheses2021,Vol.1552.DOI:10.1016/j.mehy.2021.110668

Nutrition acquisition by human immunity, transient overnutrition and the cytokine storm in severe cases of COVID-19

Yu, Boxuan Yu, Ligen Klionsky, Daniel J.
Medical hypotheses2021,Vol.1552.DOI:10.1016/j.mehy.2021.110668

Nutrition acquisition by human immunity, transient overnutrition and the cytokine storm in severe cases of COVID-19

Yu, Boxuan 1Yu, Ligen 2Klionsky, Daniel J.3
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作者信息

  • 1. Hwa Chong Inst, 661 Bukit Timah Rd, Singapore 269734, Singapore
  • 2. Nanyang Technol Univ, Talent Recruitment & Career Support Off & Bibliom, Singapore, Singapore
  • 3. Univ Michigan, Life Sci Inst, Ann Arbor, MI 48109 USA
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Abstract

The human immunity has a pivotal role in nutrition acquisition from the pathogens and damaged body tissue during the SARS-CoV-2 virus infection, which may lead to transient overnutrition in the patients, lead to lipotoxicity and further damage in non-adipose tissues, and cause hyperinflammation and cytokine storm in severe cases of COVID-19. In view of this, high-quality clinical trials on restrictive eating should be designed to investigate the possible benefits of food intake restriction on patients' recovery from COVID-19 disease.

Key words

COVID-19/Cytokine storm/Hyperinflammation/Immune system/Nutrition acquisition/Overnutrition

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出版年

2021
Medical hypotheses

Medical hypotheses

SCI
ISSN:0306-9877
被引量5
参考文献量11
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