首页|Datinolides E-I, five new withanolides with anti-inflammatory activity from the leaves of Datura inoxia Mill

Datinolides E-I, five new withanolides with anti-inflammatory activity from the leaves of Datura inoxia Mill

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Five new withanolides, datinolides E-I (1-5), and three known withanolides (6-8) were separated from Datura inoxia Mill. leaves, and datinolide E (1) was the first withanolide with C-27 connected to a nitrogen-containing group. Their structures were clarified by comprehensive spectroscopic analysis and comparison with literature. The anti-inflammatory of isolated compounds against RAW264.7 cells was investigated by the CCK8 assay.

Datura inoxia MillWithanolideAnti-inflammatory activitiesSolanaceaeAERIAL PARTS

Wu, Jia-Tong、Liu, Yan、Jiang, Yi-Kai、Wang, Si-Yi、Jiang, Chen-Yu、Algradi, Adnan Mohammed、Pan, Juan、Guan, Wei、Kuang, Hai-Xue、Yang, Bing-You

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Heilongjiang Univ Chinese Med

2022

Fitoterapia

Fitoterapia

SCI
ISSN:0367-326X
年,卷(期):2022.159
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