首页|Feeding and Growth Outcomes in Infants with Type C Esophageal Atresia Who Undergo Early Primary Repair
Feeding and Growth Outcomes in Infants with Type C Esophageal Atresia Who Undergo Early Primary Repair
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NSTL
Elsevier
Objectives To describe growth and feeding outcomes in patients with type C esophageal atresia who underwent early primary repair and to identify predictors for poor growth. Study design This single-center, retrospective, cohort study included all patients with type C esophageal atresia who underwent early primary repair from 2013 to 2019. Weight-for-age z score (WAZ) was calculated at birth, and every 6 months until 3 years postoperatively. Longitudinal median regression was used to evaluate WAZ over time. A multivariable logistic regression model explored predictors of growth outcomes. Results Of 46 infants who met the inclusion criteria, 72% were term. The median age at repair was 1.5 days of life (IQR, 1-2 days of life) and the hospital length of stay was 20 days (IQR-14, 30 days). Two patients had esophageal leak (4.3%). The median WAZ at birth was below average (-0.72; IQR, -1.37 to -0.40), but improved to reach average by 3 years (-0.025; IQR, -0.85 to 0.97, P <.001). At discharge, 72% of patients were receiving full oral nutrition, which improved to 95% by 3 years. The only independent predictor of poor growth at 1 year (WAZ < -1 [33%]) was WAZ at discharge (P =.02). Conclusions Infants with esophageal atresia who undergo early primary repair are capable of achieving standard growth curves by 3 years of age. However, poor discharge WAZ score was predictive of poor WAZ score at 1 year. Efforts to identify at-risk patients and institute targeted inpatient and outpatient nutrition interventions are needed to improve their growth trajectory.
PEDIATRIC MALNUTRITIONNUTRITION DELIVERYCHILDREN
Harrington, Amanda W.、Riebold, Jane、Hernandez, Kayla、Staffa, Steven J.、Meisner, Jay W.、Zurakowski, David、Jennings, Russell、Hamilton, Thomas、Zendejas, Benjamin
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Dept Surg,Boston Childrens Hosp
Div Gastroenterol Hepatol & Nutr,Boston Childrens Hosp
Dept Anesthesiol Crit Care & Pain Med,Boston Childrens Hosp
NSTL
Elsevier
