首页|Optimizing skin antisepsis for neonatal surgery: A quality improvement initiative
Optimizing skin antisepsis for neonatal surgery: A quality improvement initiative
扫码查看
点击上方二维码区域，可以放大扫码查看
原文链接
NSTL
Elsevier
? 2022Purpose: Surgical site infections (SSIs) are a significant determinant of morbidity in the Neonatal Intensive Care Unit (NICU). Chlorhexidine gluconate/isopropyl alcohol (CHG-IPA) skin prep has demonstrated superiority over Povidone-Iodine (PI) in preventing SSIs in adults, however FDA labeling discourages CHG use in infants <2 months. This project aimed to i) create evidence for safe CHG skin antisepsis in neonates; and ii) evaluate the safety and effectiveness of CHG skin prep for neonatal surgery. Methods: A literature review was conducted to assess the safety and effectiveness of neonatal CHG skin antisepsis. Following stakeholder engagement, a CHG surgical skin prep protocol and validated neonatal skin integrity tool to assess prep-associated skin injury were implemented in 50 consecutive, eligible neonates ≥1500 g and ≥34 weeks post conceptual age undergoing abdominal or thoracic surgery. SSI rates were compared to a matched, historical PI skin prep cohort. Results: 2%CHG-70%IPA or 0.5%CHG-70%IPA were used based on gestational age cutoffs. None of the CHG patients experienced adverse skin prep outcomes while 8% developed SSIs, compared to 14% in the historical PI cohort. Conclusion: This project engaged NICU stakeholders in quality improvement work and informed the implementation of a safe and effective CHG skin prep protocol for neonatal surgery. LOE: IV
Chlorhexidine gluconateMultidisciplinary quality improvementNeonatalNeonatal intensive care unitSkin antisepsisSurgical site infection
Carr S.、Gogal C.、Afshar K.、Ting J.、Skarsgard E.
展开 >
Faculty of Medicine University of British Columbia
Clinical Care Analyst Surgical Services and National Surgical Quality Improvement Program BC
Department of Surgery British Columbia Children's Hospital/Department of Urologic Sciences
Division of Neonatology Department of Pediatrics University of Alberta
Department of Surgery British Columbia Children's Hospital and the University of British Columbia
NSTL
Elsevier
