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Gastrointestinal disorder biomarkers

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  • NSTL
  • Elsevier
Gastrointestinal (GI) disorders refer to gastrointestinal tract conditions, ranging from dyspepsia to inflammatory bowel diseases (IBDs) and malignant tumors. Biomarkers, which are assessable indicators of the presence or severity of the disorders, are indispensable agents to diagnose GI conditions. Diagnostic biomarkers, including serological biomarkers, antibodies, immunological biomarkers, fecal biomarkers, and genetic biomarkers (Non-encoding RNAs), are investigated and categorized in this review. Furthermore, we have discussed the essential biological functions and diagnostic roles and the advantages and disadvantages of these biomarkers, besides novel genetic biomarkers such as miRNA-146a and their role in GI diseases.

BiomarkerGastrointestinal disordersInflammatory bowel diseasesmiRNAsCrohn 's diseaseINFLAMMATORY-BOWEL-DISEASEC-REACTIVE PROTEINREGULATORY T-CELLSSACCHAROMYCES-CEREVISIAE ANTIBODIESSINGLE-NUCLEOTIDE POLYMORPHISMSNONCODING RNA H19KINASE TYPE M2CROHNS-DISEASEFECAL CALPROTECTINGASTRIC-CANCER

Ranjbar, Reza、Ghasemian, Mohamad、Maniati, Mahmood、Khatami, Seyyed Hossein、Jamali, Navid、Taheri-Anganeh, Mortaza

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Mol Biol Res Ctr,Baqiyatallah Univ Med Sci

Sch Med,Ahvaz Jundishapur Univ Med Sci

Sch Med,Shahid Beheshti Univ Med Sci

Dept Lab Sci,Sirjan Sch Med Sci

Cellular & Mol Res Ctr,Urmia Univ Med Sci

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2022

10.1016/j.cca.2022.02.013

Clinica chimica acta

Clinica chimica acta

ISTP
ISSN：0009-8981
年,卷(期)：2022.530
  • 234