Abstract
? 2022 Elsevier B.V.Cu2?xS nanochains network (NCNW) with tunable diameter in the range of 5–9 nm is prepared by a self-assembly strategy. Control experiments reveal that poly (sodium 4-styrenesulfonate) plays a key role in guiding the assembly of the nanochains. The Cu2?xS NCNW demonstrates a broad localized surface plasmon resonance (LSPR) band in the near-infrared-Ⅱ region, which matches the optical window of biological tissues. The LSPR band of the Cu2?xS NCNW red-shifts and intensifies with the increase of diameter. The Cu2?xS NCNW with an average diameter of 8.7 nm exhibits a high photothermal conversion efficiency of 80.7% under 808 nm laser (0.75 W cm?2). Furthermore, the thermal effect stability of the Cu2?xS NCNW is also good. In vitro experiments demonstrate that all the nanochains possess low cell cytotoxicity. The 8.7 nm Cu2?xS NCNW own the maximum cellular uptake, and can cause> 90% apoptosis rate of Hela cells under low power density laser (808 nm, 0.75 W cm?2), demonstrating its promising application in photothermal therapy.
NSTL
Elsevier