首页|Enrichment of phenolic compounds from grape(Vitis vinifera L.)pomace extract using a macroporous resin and response surface methodology
Enrichment of phenolic compounds from grape(Vitis vinifera L.)pomace extract using a macroporous resin and response surface methodology
扫码查看
点击上方二维码区域，可以放大扫码查看
原文链接
NSTL
A green protocol was proposed for the extraction and separation of high-value phenolic compounds(PCs)from grape(Vitis vinifera L.)pomace.The most important variables for scale-up purposes including extraction time(4-16 h),temperature(40-80 ℃),and solvent-to-feed ratio(8-40 mL.g~(-1))on the extraction efficiency and yield of PCs were scrutinized by experimental design using Response Surface Methodology(RSM).The yield of PCs was quantified by monitoring the content of gallic acid(GA)and procyanidin B using the HPLC-UV analysis.To obtain an enriched extract,the optimized extract was loaded on a new designed multi-stage continuous flow adsorption column filled with a nonionic acrylic polymeric resin(LXA-10)adsorbent.The adsorption properties,including the adsorption isotherms and kinetics as well as dynamic test in term of breakthrough curve analysis have also been investigated.The optimal extraction condition was attained at 80 ℃,10 h and 20 mL.g~(-1),and extraction efficiency of 1_(0.6)7% w/w.After enrichment process,the purity of PCs in the resulting product was reached to 99%,and the yield of product respect to initial grape pomace powdered was 1.91%.These findings may have implications in the development of adjuvant supplement manufacturing with potential effect on improving immune system.Data Auailability: The authors confirm that the data used to support the findings of this study are included within the article and its Supplementary material.
NSTL
