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Point-of-care testing for sexually transmitted infections in low-resource settings
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NSTL
Elsevier
Background: Both the global incidence and the prevalence of sexually transmitted infections (STIs) continue to increase, affecting hundreds of millions of individuals, particularly in low-to middle-income countries. Although a definitive diagnosis is desirable to inform STI treatment, syndromic management is the most widely used strategy in resource-limited settings. With the development of point-of-care (POC) tests, it is important to discuss how laboratories will need to adapt to new training and supervisory roles in support of testing, which will largely be performed by peripheral clinical staff. Objectives: To discuss potential applications of STI POC tests, how they could improve existing STI control strategies and the role of clinical and reference laboratories in support of initiatives to improve STI management and control activities. Sources: Narrative literature review and expert opinion. Content: The paper outlines the current status of the STI epidemic worldwide and discusses the problems associated with current approaches to control these infections, particularly in low-resource settings. The roles of clinical and reference laboratories will need to change to provide support for POC and near-patient STI testing as these technologies are introduced into clinical as well as laboratory settings. (C) 2021 World Health Organization; licensee European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
Clinical and reference laboratoriesLow-resource settingsPoint-of-care testsPublic healthSexually transmitted infectionsPREVENTIONGONORRHEASYPHILISDISEASESDIAGNOSTICSMANAGEMENT
Vargas, S.、Calvo, G.、Qquellon, J.、Vasquez, F.、Blondeel, K.、Ballard, R.、Toskin, I
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The World Bank,WHO
Ctr Interdisciplinary Invest Sexual AIDS Soc & La,Univ Peruana Cayetano Heredia
NSTL
Elsevier
