首页|ACTIVE METABOLITES FROM THE FUNGUS Pestalotiopsis sp.YMF1.0474

ACTIVE METABOLITES FROM THE FUNGUS Pestalotiopsis sp.YMF1.0474

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The chemical constituents of the fungus Pestalotiopsis sp.YMF1.0474 were studied.Five compounds,including a new pestalrone С(1)and four known compounds,namely,6-[1-hydroxy-(15)-pentyl]-4-те1Ьоху-(6S)-2H,5H-ругап-2-опе(2),LL-P880β(3),pestalrone A(4),and methyl(E)-octadec-9-enoate(5),were isolated from the culture broth of strain YMFI.0474.Compounds 1-4 showed acetylcholinesterase(AChE)inhibitory activity with IC_(50)33.90,81.54,16.43,and 95.22 μМ,respectively.

Pestalotiopsis sp.α-pyrone analogueacetylcholinesterase inhibitory activity

Cheng-Mang Liu、Ya-Li Wang、Xin Wang

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State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan,and Key Laboratory for Microbial Resources of the Ministry of Education,Yunnan University,650091,Kunming,P.R.China

2021

Химия природных соединений

Химия природных соединений

ISSN:0023-1150
年,卷(期):2021.(2)