Fitoterapia2022,Vol.1587.DOI:10.1016/j.fitote.2022.105160

Discovery of ent-kaurane diterpenoids, characteristic metabolites of Isodon species, from an endophytic fungal strain Geopyxis sp. XY93 inhabiting Isodon parvifolia

Xia J.-N. Hu K. Su X.-Z. Tang J.-W. Li X.-N. Sun H.-D. Puno P.-T.
Fitoterapia2022,Vol.1587.DOI:10.1016/j.fitote.2022.105160

Discovery of ent-kaurane diterpenoids, characteristic metabolites of Isodon species, from an endophytic fungal strain Geopyxis sp. XY93 inhabiting Isodon parvifolia

Xia J.-N. 1Hu K. 1Su X.-Z. 1Tang J.-W. 1Li X.-N. 1Sun H.-D. 1Puno P.-T.1
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作者信息

  • 1. State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of Botany Chinese Academy of Sciences Yunnan Key Laboratory of Natural Medicinal Chemistry
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Abstract

? 2022 Elsevier B.V.Isogeopyxins A–C (1–3), three new diterpenoids with ent-kaurane, ent-pimarane, and ent-abietane scaffolds, respectively, along with six known ent-kauranoids, were isolated from the fermentation culture of Geopyxis sp. XY93 inhabiting the leaves of Isodon parvifolia. Their structures were elucidated by interpretation of spectroscopic data, and single crystal X-ray diffraction. It marks the first time that ent-kauranoids, characteristic metabolites of Isodon species, have been isolated from an associated endophytic fungus.

Key words

Cytotoxic activities/Endophytes/ent-Kaurane diterpenoids/Geopyxis sp./Isodon parvifolia

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出版年

2022
Fitoterapia

Fitoterapia

SCI
ISSN:0367-326X
被引量2
参考文献量29
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