首页|Discovery of ent-kaurane diterpenoids, characteristic metabolites of Isodon species, from an endophytic fungal strain Geopyxis sp. XY93 inhabiting Isodon parvifolia

Discovery of ent-kaurane diterpenoids, characteristic metabolites of Isodon species, from an endophytic fungal strain Geopyxis sp. XY93 inhabiting Isodon parvifolia

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? 2022 Elsevier B.V.Isogeopyxins A–C (1–3), three new diterpenoids with ent-kaurane, ent-pimarane, and ent-abietane scaffolds, respectively, along with six known ent-kauranoids, were isolated from the fermentation culture of Geopyxis sp. XY93 inhabiting the leaves of Isodon parvifolia. Their structures were elucidated by interpretation of spectroscopic data, and single crystal X-ray diffraction. It marks the first time that ent-kauranoids, characteristic metabolites of Isodon species, have been isolated from an associated endophytic fungus.

Cytotoxic activitiesEndophytesent-Kaurane diterpenoidsGeopyxis sp.Isodon parvifolia

Xia J.-N.、Hu K.、Su X.-Z.、Tang J.-W.、Li X.-N.、Sun H.-D.、Puno P.-T.

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State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of Botany Chinese Academy of Sciences Yunnan Key Laboratory of Natural Medicinal Chemistry

2022

Fitoterapia

Fitoterapia

SCI
ISSN:0367-326X
年,卷(期):2022.158
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