首页|Oreocharioside A-G, new acylated C-glycosylflavones from Oreocharis auricula (Gesneriaceae)

Oreocharioside A-G, new acylated C-glycosylflavones from Oreocharis auricula (Gesneriaceae)

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  • NSTL
  • Elsevier
? 2022Seven new acylated C-glycosylflavones, oreocharioside A-G, together with two known compounds were isolated from the whole plant of Oreocharis auricula. Their structures were characterized by the comprehensive analysis of their NMR, IR, UV, CD spectra and HRESIMS data. All the new compounds were evaluated for the antioxidant and anti-inflammatory activities. The results showed that compounds 1 and 2 had significant DPPH and ABTS radical scavenging activities, with the IC50 values of 0.32–3.20 μg/mL. Compounds 2 and 3 exhibited the higher potency among all the new compounds in reducing TNF-α production.

Acylated C-glycosylflavonesAnti-inflammatory activityAntioxidant activityOreocharis auricula

Xie R.-X.、Chen J.-L.、Huang L.-J.、Hao X.-J.、Gu W.、Zhou L.-Q.、Fu X.-J.、Yuan C.-M.、Hu Z.-X.

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State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University

2022

10.1016/j.fitote.2022.105158

Fitoterapia

Fitoterapia

SCI
ISSN：0367-326X
年,卷(期)：2022.158
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