首页|Latanoprost-loaded cyclodextrin microaggregate suspension eye drops for enhanced bioavailability and stability

Latanoprost-loaded cyclodextrin microaggregate suspension eye drops for enhanced bioavailability and stability

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  • NSTL
  • Elsevier
Objective: The bioavailability of conventional eye drops is very low due to different physiological barriers. Commercial latanoprost (LAT) eye drops (Xalatan (R)) need to be refrigerated and protected from light. The purpose of this study was to develop novel LAT eye drops to improve ocular bioavailability and stability.

Latanoprostgamma-cyclodextrinCyclodextrin aggregatesSuspension eye dropsBioavailabilityStability

Zhou, Xiangying、Li, Xiaolin、Xu, Jiangmin、Cheng, Yanju、Cao, Feng

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China Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, 24 Tongjia Xiang, Nanjing 210009, Peoples R China

Chia Tai Tianqing Pharmaceut Grp Co Ltd, Dept Biol, R&D Ctr, 1099 Fuying Rd, Nanjing 211122

2021

10.1016/j.ejps.2021.105758

European journal of pharmaceutical sciences

European journal of pharmaceutical sciences

ISTP
ISSN：0928-0987
年,卷(期)：2021.160
  • 6
  • 33