Phytochemistry2022,Vol.19313.DOI:10.1016/j.phytochem.2021.112987

Alkaloids from Picrasma quassioides: An overview of their NMR data, biosynthetic pathways and pharmacological effects

Chen Qian-wen Ye Xiao Liu Xiao-qian Liang Yao-hua Feng Wei-hong Li Chun Wang Zhi-min
Phytochemistry2022,Vol.19313.DOI:10.1016/j.phytochem.2021.112987

Alkaloids from Picrasma quassioides: An overview of their NMR data, biosynthetic pathways and pharmacological effects

Chen Qian-wen 1Ye Xiao 1Liu Xiao-qian 1Liang Yao-hua 1Feng Wei-hong 1Li Chun 1Wang Zhi-min1
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作者信息

  • 1. China Acad Chinese Med Sci
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Abstract

Picrasma quassioides, a member of the Simaroubaceae family, is the subject of research in numerous pharmacological and chemical studies. This plant mainly contains alkaloids, quassinoids and terpenoids. These molecules exhibit various pharmacological benefits, such as anti-inflammatory, anticancer, and anti-viral effects, on the cardiovascular system. Alkaloids make up the majority of these molecules. This review describes 127 alkaloid substances from P. quassioides. These alkaloids can be divided into the following classes: beta-carbolines, canthinones and alkaloid dimers. A compilation of their nuclear magnetic resonance spectroscopy data and possible biosynthetic pathways of these compounds and the pharmacological effects of P. quassioides are also included.

Key words

Picrasma quassioides/Alkaloids/NMR/Pharmacological effects/BETA-CARBOLINE ALKALOIDS/CYCLIC-AMP PHOSPHODIESTERASE/D. DON BENN./IN-VITRO/STEMS/INHIBITION/4-METHOXY-5-HYDROXYCANTHIN-6-ONE/EXTRACT/CANCER

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出版年

2022
Phytochemistry

Phytochemistry

CCR
ISSN:0031-9422
被引量5
参考文献量68
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