首页|Diagnostic Code-Based Screening for Identifying Children with Primary Hyperoxaluria
Diagnostic Code-Based Screening for Identifying Children with Primary Hyperoxaluria
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Before hypotheses could be generated, observation and data were needed. These conjectures could then be tested and their results collated. The interpretation of these new data restarts the cycle; hypotheses are discarded, revised, and reformulated. New tests are run and so on and so forth. Arthur Conan Doyle’s Sherlock Holmes, the famous fictional detective notable for his deductive acumen, identified a key weakness to this method: it needed reliable observations. In “The Adventure of the Copper Beeches,” he exclaims “Data! Data! Data! . I can’t make bricks without clay.”1 The near ubiquity of the computers, the Internet, and electronic medical records offer the hope that data could be gathered from vast physical and virtual networks. Reports of rare and unusual conditions that would take hundreds of years to collate by any single practitioner or institution could be gathered easily. Common conditions could likewise be accumulated and subjected to new analysis.