Phytochemistry2022，Vol.1999.DOI:10.1016/j.phytochem.2022.113171

Eight undescribed steroidal saponins including an unprecedented 16, 26-epoxy-furostanol saponin from Solanum xanthocarpum and their cytotoxic activities

Xu Z.-P. Liu Y. Wang S.-Y. Li Z.-W. Li X.-M. Lu D.-X. Pan J. Kuang H.-X. Yang B.-Y.
Phytochemistry2022，Vol.1999.DOI:10.1016/j.phytochem.2022.113171
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  • NSTL
  • Elsevier

Eight undescribed steroidal saponins including an unprecedented 16, 26-epoxy-furostanol saponin from Solanum xanthocarpum and their cytotoxic activities

Xu Z.-P. 1Liu Y. 1Wang S.-Y. 1Li Z.-W. 1Li X.-M. 1Lu D.-X. 1Pan J. 1Kuang H.-X. 1Yang B.-Y.1
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作者信息

  • 1. Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine) Ministry of Education Heilongjiang University of Chinese Medicine
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Abstract

? 2022 Elsevier LtdEight undescribed steroidal saponins named solasaponins A-H were isolated from the fruits of Solanum xanthocarpum, including an unusual 16,26-epoxy-furostanol saponin, two furostanol saponins, three isospirostanol saponins, two pseudo-spirostanol saponins. The structures of all compounds were elucidated by extensive spectroscopic data analyses (1D, 2D NMR, and HRESIMS) combined with physico-chemical analysis methods (acid hydrolysis, optical rotation, and IR). The cytotoxicities of all compounds in vitro against two human cancer cell lines (A-549 and HepG2) were evaluated by CCK-8 assay.

Key words

16/26-Epoxy-furostanol saponin/Solanaceae/Solanum xanthocarpum/Solasaponin/Sterides/Steroidal glycosides

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出版年

2022
Phytochemistry

Phytochemistry

CCR
ISSN：0031-9422
被引量1
参考文献量37
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