首页|Eight undescribed steroidal saponins including an unprecedented 16, 26-epoxy-furostanol saponin from Solanum xanthocarpum and their cytotoxic activities

Eight undescribed steroidal saponins including an unprecedented 16, 26-epoxy-furostanol saponin from Solanum xanthocarpum and their cytotoxic activities

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  • NSTL
  • Elsevier
? 2022 Elsevier LtdEight undescribed steroidal saponins named solasaponins A-H were isolated from the fruits of Solanum xanthocarpum, including an unusual 16,26-epoxy-furostanol saponin, two furostanol saponins, three isospirostanol saponins, two pseudo-spirostanol saponins. The structures of all compounds were elucidated by extensive spectroscopic data analyses (1D, 2D NMR, and HRESIMS) combined with physico-chemical analysis methods (acid hydrolysis, optical rotation, and IR). The cytotoxicities of all compounds in vitro against two human cancer cell lines (A-549 and HepG2) were evaluated by CCK-8 assay.

1626-Epoxy-furostanol saponinSolanaceaeSolanum xanthocarpumSolasaponinSteridesSteroidal glycosides

Xu Z.-P.、Liu Y.、Wang S.-Y.、Li Z.-W.、Li X.-M.、Lu D.-X.、Pan J.、Kuang H.-X.、Yang B.-Y.

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Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine) Ministry of Education Heilongjiang University of Chinese Medicine

2022

10.1016/j.phytochem.2022.113171

Phytochemistry

Phytochemistry

CCR
ISSN：0031-9422
年,卷(期)：2022.199
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