首页|Could Galectin-3 be a key player in the etiology of neuromyelitis optica spectrum disorder?
Could Galectin-3 be a key player in the etiology of neuromyelitis optica spectrum disorder?
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NSTL
Elsevier
Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic, inflammatory, demyelinating disorder of the central nervous system (CNS) characterized primarily by transverse myelitis (TM) and optic neuritis (ON)。 Serum antibodies of the IgG class to the water channel protein aquaporin-4 (AQP4) are associated with NMOSD in most cases。 These antibodies are thought to cause functional abnormality or changed expressional pattern of AQP4 channel proteins in the CNS lesions。
Galectin-3NMOSDMicrogliaInflammationEtiology
Ramakrishnan, Pooja
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