Tetrahedron letters2022，Vol.934.DOI:10.1016/j.tetlet.2022.153691

Pregnane steroids from the twigs and leaves of Strophanthus divaricatus and their cytotoxic activities

An, Pei-Pei Cui, Yong-Sheng Shi, Qiong-Yu Ren, Yu-Hao Wu, Pei-Qian Liu, Qun-Fang Liu, Hong-Chun Zhou, Bin Yue, Jian-Min
Tetrahedron letters2022，Vol.934.DOI:10.1016/j.tetlet.2022.153691
✕
  • NSTL
  • Elsevier

Pregnane steroids from the twigs and leaves of Strophanthus divaricatus and their cytotoxic activities

An, Pei-Pei 1Cui, Yong-Sheng 1Shi, Qiong-Yu 2Ren, Yu-Hao 2Wu, Pei-Qian 1Liu, Qun-Fang 2Liu, Hong-Chun 2Zhou, Bin 2Yue, Jian-Min1
扫码查看

作者信息

  • 1. Nanjing Univ Chinese Med
  • 2. Chinese Acad Sci
  • 折叠

Abstract

Four new pregnanes (1-4), including one 21-norpregnane (4), together with two known pregnanes (5 and 6), were isolated from the twigs and leaves of Strophanthus divaricatus. Their structures were elucidated on the basis of spectroscopic data analysis, ECD data, and X-ray crystallographic study. The cytotoxic activities of these pregnanes against two human cancer cell lines were evaluated. CO 2022 Elsevier Ltd. All rights reserved.

Key words

Strophanthus divaricatus/Pregnanes/Structural elucidation/Cytotoxic activity/X-ray crystallography

引用本文复制引用

出版年

2022
Tetrahedron letters

Tetrahedron letters

CCR
ISSN：0040-4039
被引量1
参考文献量14
段落导航相关论文