Abstract
An organophotocatalytic ring opening/remote trifluoromethylselenolation of cycloalkanols is reported. This reaction proceeds the radical ring-opening in a photocatalytic system without metal catalysis under mild conditions, followed by the formation of the remote C(sp3)-SeCF3 bond in the presence of PhSO2SeCF3. The reaction brings out highly reactive to prepare trifluoromethylselenolated carbonyl compounds, suitable for a variety of aryl cyclic alcohols, while compatible with different ring systems with high yield, including 26 examples, the highest isolated yield of 93%. (c) 2022 Elsevier Ltd. All rights reserved.
NSTL
Elsevier