首页|Anacardic 6-pentadecyl salicylic acid induces apoptosis in breast cancer tumor cells, immunostimulation in the host and decreases blood toxic effects of taxol in an animal model

Anacardic 6-pentadecyl salicylic acid induces apoptosis in breast cancer tumor cells, immunostimulation in the host and decreases blood toxic effects of taxol in an animal model

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Many antineoplastic agents induce myelosuppression and leukopenia as secondary effects in patients. The development of anticancer agents that simultaneously provoke antitumor immune response represents an important therapeutic advance. The administration of 6-pentadecyl salicylic acid (6SA) contributes to the antitumor immunity using 4T1 breast cancer cells in Balb/c female mice, with Taxol as a positive control and in cotreatment with 6SA (6SA + Taxol; CoT).

Anacardic acidAntitumoralImmunomodulationLeukopeniaMyelosuppression

Gnanaprakasam, J. N. Rashida、Lopez-Banuelos, Laura、Vega, Libia

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Natl Polytech Inst, Ctr Res & Adv Studies, Dept Toxicol, Ave IPN 2508, Mexico City 07360, DF, Mexico

2021

Toxicology and Applied Pharmacology

Toxicology and Applied Pharmacology

SCI
ISSN:0041-008X
年,卷(期):2021.410
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