Organic process research & development2022,Vol.26Issue(9) :50.DOI:10.1021/acs.oprd.2c00161

Synthesis and Applications of Periodate for Fine Chemicals and Important Pharmaceuticals

Kai Donsbach Sebastian Arndt Philipp J.Kohlpaintner
Organic process research & development2022,Vol.26Issue(9) :50.DOI:10.1021/acs.oprd.2c00161

Synthesis and Applications of Periodate for Fine Chemicals and Important Pharmaceuticals

Kai Donsbach 1Sebastian Arndt 2Philipp J.Kohlpaintner3
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作者信息

  • 1. Virginia Commonwealth University,College of Engineering,Medicines for All Institute,Richmond,Virginia 23284-3068,United States
  • 2. Department of Chemistry,Johannes Gutenberg University Mainz,5S128 Mainz,Germany
  • 3. Department of Chemistry,Johannes Gutenberg University Mainz,53128 Mainz,Germany
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Abstract

An emerging interest for the application of periodate in the synthesis of active pharmaceutical ingredients(APIs) and for the valorization of renewable feedstock is eminent.However,periodate exhibits a high molecular mass,is expensive compared to other common bulk-oxidizers and is used only reluctantly in technical applications.Recently,a new and green electrochemical synthesis was established.The preparation and regeneration method for periodate lowers costs and enables the use of periodate in the synthesis of regulated products.This review will briefly introduce the key innovations in the electrochemical synthesis of periodate and will survey the most important applications of periodate in the production of fine chemicals.

Key words

periodate/electrolysis/Malaprade oxidation/Lemieux-Johnson oxidation/active pharmaceutical ingredients

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出版年

2022
Organic process research & development

Organic process research & development

CCR
ISSN:1083-6160
被引量10
参考文献量561
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