Abstract
We report a significantly faster and greener technique for parallel chemical reaction work-ups. Unlike conventional liquid-liquid extraction-based work-ups, we use a cylindrical-shaped polyurethane foam 'sponge' as a "foam solvent" to extract organic products from a quenched aqueous reaction mixture. The foam, loaded with organic products, serves as a convenient input for flash chromatographic separa-tions (and, therefore, we call it 'Fast2Flash'). This technique displayed a high efficiency for separating an organic phase from an aqueous phase, eliminating tedious and solvent-wasting liquid-liquid extractions and emulsion formation. Moreover, parallel and automatic operations are facilitated.(c) 2022 Published by Elsevier Ltd.
NSTL
Elsevier