首页|The effect of aerobic exercise on the lipophagy of adipose tissue in obese male mice
The effect of aerobic exercise on the lipophagy of adipose tissue in obese male mice
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NSTL
Elsevier
? 2022 Elsevier B.V.This article explores the obesity state and the changes in the level of lipophagy in adipose tissue after exercise to lose weight, so as to provide direction and basis for theoretical research on obesity prevention and control. We established a high-fat diet model of obese mice, and applied exercise intervention and intraperitoneal injection of chloroquine to inhibit autophagy. Long-term high-fat diet can cause obesity in mice, and the process of lipophagy is inhibited, which may be one of the reasons for fat accumulation. Eight weeks of aerobic exercise can effectively reduce the weight of obese mice and promote lipolysis; this process is mainly completed by lipase decomposition, in addition to require the participation of the lipophagy process.
AdiposeExerciseLipophayObesityRab7
Ma T.、Li R.、Li G.、Hai Y.、Li T.、Bian Y.
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The College of Kinesiology Shenyang Sport University
Physical Education Department Shenyang University of Chemical Technology Shenyang Economic and Technological Development Zone
Department of Postgraduate Shenyang Sport University
College of Food Science Shenyang Agricultural University
NSTL
Elsevier
