首页|An efficient one pot three-component synthesis of 2,4,6-triarylpyridines using triflimide as a metal-free catalyst under solvent-free conditions
An efficient one pot three-component synthesis of 2,4,6-triarylpyridines using triflimide as a metal-free catalyst under solvent-free conditions
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NSTL
Royal Soc Chemistry
A simple and efficient protocol developed for one pot three-component synthesis of 2,4,6-triarylpyridines from aromatic aldehydes, substituted acetophenones and ammonium acetate using the versatile super Bronsted acid triflimide ({HNTf2) as an effective catalyst is described. The reactions proceed well in the presence of 1 mol% of HNTf2 at 80 degrees C under solvent-free conditions and provide the corresponding triarylpyridines in good to excellent yields. The method reported has several advantages such as a metal-free and commercially available catalyst, mild reaction conditions and lower loading of catalyst.
Du, Juan、Wei, Fenyan、Chen, Qi、Wang, Xiaomei、Wang, Hongshe、Zhao, Weixing
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Baoji Univ Arts & Sci, Coll Chem & Chem Engn, Baoji 721013, Peoples R China
NSTL
Royal Soc Chemistry
