首页|Five new diterpenoid alkaloids from Aconitum sczukinii Turcz.

Five new diterpenoid alkaloids from Aconitum sczukinii Turcz.

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? 2021 Phytochemical Society of EuropeTen diterpenoid alkaloids, including five new ones, sczukiniline A–E (1-5), were isolated from the root of Aconitum sczukinii. Their structures were elucidated based on the interpretation of spectroscopic data (HRESI-MS, IR, 1D- and 2D-NMR). Among the five new diterpenoid alkaloids, 1-3 are hetidine-type C20-diterpenoid alkaloids, while compounds 4 and 5 are lycoctonine-type C19-diterpenoid alkaloids. Noteworthily, sczukiniline A (1) features a novel ester group between C-12 and C-14, forming a D ring containing a lactone structure, resulting in a new skeleton of hetidine-type C20-diterpenoid alkaloid.

Aconitum sczukinii Turcz.Diterpenoid alkaloidRanunculaceaeSczukiniline

Li J.-M.、Li X.、Gao F.、Chen L.、Zhou X.-L.、Cai L.、Liang X.-X.

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School of Life Science and Engineering Southwest Jiaotong University

School of Chemical Science and Technology Yunnan University

Natural Medicine Research Center College of Veterinary Medicine Sichuan Agricultural University

2022

Phytochemistry Letters

Phytochemistry Letters

SCI
ISSN:1874-3900
年,卷(期):2022.47
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