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Role of extracellular vesicles in intercellular communication during reproduction
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NSTL
Wiley
The mammalian reproduction is a process of controlled cellular growth and development regulated by constant communication between the gametes, the subsequent embryo and the maternal system. Extracellular vesicles (EVs) are involved in these communications to a significant degree from the gamete production and maturation to fertilization, embryo development and implantation. They regulate the cellular physiology and the immune reaction to bring about a favourable environment for a successful pregnancy. Deciphering the mechanisms employed in EV-mediated embryo maternal communication could improve our knowledge in mammalian reproduction and increase the efficiency of animal breeding.
embryo-maternal communicationextracellular vesiclesimmune regulationintercellular signallingmaternal recognition of pregnancy
Kasun Godakumara、Keerthie Dissanayake、Mohammad Mehedi Hasan、Suranga. P. Kodithuwakku、Alireza Fazeli
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Department of Pathophysiology, Institute of Biomedicine and Translational Medicine, Faculty of Medicine, Tartu University, Tartu, Estonia
Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, Estonia
NSTL
Wiley
