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Computational Psychiatry Needs Time and Context

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  • NSTL
  • Annual Reviews
Why has computational psychiatry yet to influence routine clinical practice? One reason may be that it has neglected context and temporal dynamics in the models of certain mental health problems. We develop three heuristics for estimating whether time and context are important to a mental health problem: Is it characterized by a core neurobiological mechanism? Does it follow a straightforward natural trajectory? And is intentional mental content peripheral to the problem? For many problems the answers are no, suggesting that modeling time and context is critical. We review computational psychiatry advances toward this end, including modeling state variation, using domain-specific stimuli, and interpreting differences in context. We discuss complementary network and complex systems approaches. Novel methods and unification with adjacent fields may inspire a new generation of computational psychiatry.

computational psychiatrynetwork approachstate versus traitdomain specificitytemporal dynamicsfunctional analysisMAJOR DEPRESSIVE DISORDERHARMFUL DYSFUNCTIONCOGNITIVE DEFICITSSTRIATAL DOPAMINENEGATIVE SYMPTOMSSTATEMODELREWARDPSYCHOPATHOLOGYDIMENSIONS

Hitchcock, Peter F.、Fried, Eiko, I、Frank, Michael J.

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Brown Univ

Leiden Univ

2022

10.1146/annurev-psych-021621-124910

Annual Review of Psychology

Annual Review of Psychology

SCI
ISSN：0066-4308
年,卷(期)：2022.73
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