Enantioselective Trost alkynylation with 2E,4E-5-bromo-2,4-pentadienal
Ervik, Karina 1Hansen, Trond Vidar1
扫码查看
点击上方二维码区域，可以放大扫码查看
作者信息
1. Univ Oslo
折叠
Abstract
The synthetically useful aldehyde 2E,4E-5-bromo-2,4-pentadienal was subjected to the enantioselective Trost alkynylation protocol, yielding highly functionalized propargylic secondary alcohols in an enantioselective manner. In most cases, the isolated yields and enantiomeric excess of the products were modest to high, but several products were formed in both high yields and enantiomeric excess. (C) 2022 The Author(s). Published by Elsevier Ltd.
NSTL
Elsevier