Tetrahedron letters2022，Vol.904.DOI:10.1016/j.tetlet.2021.153614

Oxone?-mediated halocyclization/demethylation of 2-alkynylthioanisoles with sodium halides towards 3-halobenzo[b]thiophenes

Chen X. Zhang Z. Sun T. Cai T. Shang T. Luo Y. Yu G. Shen H. Cai H. Gao Y. Wu G. Hei Y. Li E. Fan G.
Tetrahedron letters2022，Vol.904.DOI:10.1016/j.tetlet.2021.153614
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  • NSTL
  • Elsevier

Oxone?-mediated halocyclization/demethylation of 2-alkynylthioanisoles with sodium halides towards 3-halobenzo[b]thiophenes

Chen X. 1Zhang Z. 1Sun T. 1Cai T. 1Shang T. 1Luo Y. 1Yu G. 1Shen H. 1Cai H. 2Gao Y. 3Wu G. 4Hei Y. 4Li E. 4Fan G.4
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作者信息

  • 1. College of Chemistry and Chemical Engineering Shaoxing University
  • 2. Ningbo Academy of Product and Food Quality Inspection (Ningbo Fiber Inspection Institute)
  • 3. Key Laboratory of Coal to Ethylene Glycol and Its Related Technology Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences
  • 4. Zhejiang Medicine Co Ltd
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Abstract

? 2021 Elsevier LtdAn efficient and practical protocol for the Oxone?-mediated halocyclization/demethylation of 2-alkynylthioanisoles towards valuable 3-halobenzo[b]thiophenes is described. Structurally diverse 3-halobenzothiophenes were obtained in good to excellent yields under mild reaction conditions.

Key words

2-Alkynylthioanisoles/3-Halobenzo[b]thiophenes/Demethylation/Halocyclization/Heterocycles

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出版年

2022
Tetrahedron letters

Tetrahedron letters

CCR
ISSN：0040-4039
被引量3
参考文献量46
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