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Cytotoxic constituents of Viscum coloratum

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Phytochemical studies on Viscum coloratum have resulted in the isolation of nineteen compounds. The structures of the isolated compounds were identified on the basis of 1D, 2D NMR and HR-ESI-Q-TOF-MS. Pachypodol (4) and ombuine (6) were characterized in the family Loranthaceae for the first time. 1,7-Bis(4-hydroxyphenyl)-1,4-heptadien-3-one (8) and 5-hydroxy-3,7,3'-trimethoxyflavone-4'-O-β-D-glucoside (13) were two new natural compounds, which exhibited cytotoxic activities against four human tumour cell lines (HeLa, SGC-7901, MCF-7, and U251).

Cytotoxic activitiesDiarylheptanoidsViscum coloratum

Zhao, Y.L.、Wang, X.Y.、Sun, L.X.、Fan, R.H.、Bi, K.S.、Yu, Z.G.

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Department of Pharmaceutical Analysis, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China

Beijing TIDE Pharmaceutical Co., Ltd, Beijing Economic Technological Development Zone, Beijing 100176, China

2012

Zeitschrift fur Naturforschung

Zeitschrift fur Naturforschung

ISSN:0939-5075
年,卷(期):2012.67(3/4)